Michigan vs. Oregon Prediction, Odds, Picks For College Football Week 11

The No. 16 Oregon Ducks face the Michigan Wolverines on Saturday in a Week 11 college football matchup on FS1.

Let’s take a look at the odds for Michigan vs. No. 16 Oregon at DraftKings Sportsbook as of Nov. 14.

This page may contain affiliate links to legal sports betting partners. If you sign up or place a wager, FOX Sports may be compensated. Read more about Sports Betting on FOX Sports.

Moneyline

• Michigan: +340
• Oregon: -440

Spread

• Michigan +11.5: -115
• Oregon -11.5: -105

Over/Under

• Over 38.5: -105
• Under 38.5: -115

From FOX Sports Research: 

• Michigan has failed to score 20 points or more in six of its nine games this season.
• Oregon has the second-highest scoring offense in the Big Ten, averaging 34.1 points a game.
• Michigan and Oregon have met just met six times before and both have won three times.

How to Watch Michigan vs. No. 16 Oregon 

• Date: Saturday, Nov. 14, 2026
• Time: 3:30 p.m. ET
• TV: FS1
• Stream: Watch 3 days free on FOX One, FOXSports.com, FOX Sports App
• Location: Autzen Stadium, Eugene, OR